NFL Week 2 odds: How to bet Cardinals-Raiders, choose

AFC West meets NFC East in Week 2 of 2022 NFL season.

Arizona Cardinals head to Nevada this week to take on the Las Vegas Raiders at 4:25 p.m. Sunday at Allegiant Stadium.

The Cardinals are coming off a bad 44-21 loss to the Kansas City Chiefs in which they looked nonchalant. With new contracts for the general manager, coach and quarterback, a bit more effort is required. Hopefully they can get an edge for this week’s game.

The Raiders are also coming off a loss to the Los Angeles Chargers but played with much more enthusiasm, losing just 24-19. However, it wasn’t all peaches and cream as Derek Carr threw three interceptions and was sacked six times.

Here’s everything you need from a Cardinals-Raiders game betting perspective, point spread, moneyline, total over/under and expert pick (odds via FOX Bet):

RELATED: How patient can Aaron Rodgers be?

Arizona Cardinals @ Las Vegas Raiders (4:25 p.m., CBS)

Point spread: Las Vegas -5.5 (Raiders favored to win by more than 5.5 points, otherwise Cardinals cover)
Money line: Las Vegas -278 favorites to win (bet $10 to win $13.60 in total); Arizona +205 underdogs to win (bet $10 to win $30.50 total)
Over/under total score: 51.5 points scored by both teams combined

Arizona Cardinals


Las Vegas Raiders


Vikings and Ravens highlight Colin’s top 10 teams ahead of Week 2 | THE HERD

Vikings and Ravens highlight Colin's top 10 teams ahead of Week 2 |  THE HERD

After an exciting start to the NFL season, Colin Cowherd reveals his top 10 teams heading into Week 2, including the Denver Broncos, Los Angeles Rams (despite their losses) and Minnesota Vikings. Who should be in or out of Colin’s top 10 list?

Pick by betting analyst Sam Panayotovich:

After encountering a buzzsaw from Patrick Mahomes in Week 1, the Cardinals have now hit the highway to take on the new-look Raiders in the desert.

And believe me, I say “new look” with irony. Sure, Las Vegas added Davante Adams to their offense, but Derek Carr is still Derek Carr and the Raiders’ pass defense is still a serious concern.

Silver and black will have trouble slowing Kyler Murray’s arms and legs and I expect a lot more from AJ Green and Hollywood Brown. Arizona also hopes slot catcher Rondale Moore can put them on.

Take the stitches in what feels like a back and forth slant.

PICK: Cardinals (+6 at FOX Bet at pick time) to lose by less than 6 points (or win outright)

Are you ready for the NFL season? If so, head to FOX Bet for all your bets.

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